Two quick-fire goals before half time were enough for Wycombe to clinch a 2-0 win at Newport.
Peter Murphy scored on his debut and Paris Cowan-Hall followed in the space of four minutes.
But it took a resolute defensive display to hand Wanderers a perfect start to the new campaign having survived relegation from the Football League last season on goal-difference.
The goals came against the run of play as Newport dominated the first half but failed to make it count.
Mark Byrne and Mike Flynn shot straight at Matt Ingram before Chris Zebroski was booked for a foul on Joe Jacobson.
Wycombe snatched the lead on 41 minutes when Murphy poked-in Max Kretzschmar's corner at the near post.
It was the defender's first competitive goal since his summer arrival from Accrington Stanley.
Cowan-Hall then doubled the Chairboys' lead just three minutes later.
The striker was unmarked as he raced onto Sam Wood's pass to side-foot past Lenny Pidgeley.
The second-half was a similar story as Newport had most of the possession but failed to break down a determined Wycombe defence.